AI in Drug Discovery Glossary, 2020 Edition

The following was submitted to the Journal of Medicinal Chemistry as a mini-perspective for their special issue on AI in drug discovery. I leave it to the reader to judge whether they were right to reject it forthwith.

The breadth of the field of artificial intelligence (AI) in drug discovery …

2019 Early Detection Mid-Year Roundup, Part III: Clinical Performance and Economics

The shocking conclusion to a series on advances in early detection liquid biopsy from 2019H1:

  1. Part I: Tumor fraction still matters
  2. Part II: Technical advances from Grail and Guardant
  3. Part III: Clinical Performance and Economics

In the previous installments of this series, I’ve briefly reviewed some of the key …

Featured on Tech Tonics Podcast

Many thanks to Lisa Suennen and David Shaywitz for having me on Tech Tonics recently! My interview with them came out today. Listen to it on Connected Social Media or through your podcast app.

In it, I discuss with Lisa and David my work in computational biology, genetics, and the …

2019 Early Detection Mid-Year Roundup, Part II: Technology

Part of a series on advances in early detection liquid biopsy from 2019H1:

  1. Part I: Tumor fraction still matters
  2. Part II: Technical advances from Grail and Guardant

With the data I reviewed in the first post in the series it seems fair to say that everyone’s now agreed that …

Mid-2019 Early Detection Roundup, Part I: Tumor Fraction

The first half of the year is always exciting in the cancer world between results presented at AACR in April and ASCO in June, making it a good time to review the state of early detection science in mid-2019. This is long, so I’ll break it up into a …